3 You’re taking rifampin
The antibiotic rifampin can undermine hormonal contraception, including the pill, the patch (Ortho Evra), or the vaginal ring (NuvaRing).
Some anticonvulsants, oral medications for yeast infections, HIV drugs, and the herbal supplement St. John’s wort can also be a problem for these types of birth control, as well as for contraceptive implants (Implanon), according to Planned Parenthood.
Bottom line? Check with your doctor about possible interactions and medications that can make your birth control less effective.